Diffuse cutaneous mastocytosis

General Information (adopted from Orphanet):

Synonyms, Signs: DCM
Diffuse cutaneous maculopapulous mastocytosis
Number of Symptoms 15
OrphanetNr: 79456
OMIM Id:
ICD-10: Q82.2
UMLs: C0024901
MeSH:
MedDRA: 10012812
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Not applicable
[Orphanet]
Age of onset: Neonatal
Infancy
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Cutaneous mastocytosis
 -Rare allergic disease
 -Rare hematologic disease
 -Rare oncologic disease
 -Rare skin disease

Symptom Information: Sort by abundance 

1
 (HPO:0002024) Malabsorption Occasional [Orphanet] 142 / 7739
2
 (HPO:0002239) Gastrointestinal hemorrhage Occasional [Orphanet] 97 / 7739
3
 (HPO:0002240) Hepatomegaly Occasional [Orphanet] 467 / 7739
4
 (HPO:0200037) Skin vesicle Very frequent [Orphanet] 102 / 7739
5
 (HPO:0000989) Pruritus Frequent [Orphanet] 111 / 7739
6
 (HPO:0001072) Thickened skin Frequent [Orphanet] 87 / 7739
7
 (HPO:0001000) Abnormality of skin pigmentation Frequent [Orphanet] 105 / 7739
8
 (HPO:0010783) Erythema Very frequent [Orphanet] 138 / 7739
9
 (HPO:0001933) Subcutaneous hemorrhage Frequent [Orphanet] 50 / 7739
10
 (HPO:0001025) Urticaria Frequent [Orphanet] 73 / 7739
11
 (HPO:0002615) Hypotension Frequent [Orphanet] 52 / 7739
12
 (HPO:0001909) Leukemia Occasional [Orphanet] 46 / 7739
13
 (HPO:0100495) Mastocytosis Very frequent [Orphanet] 14 / 7739
14
 (HPO:0100326) Immunologic hypersensitivity Occasional [Orphanet] 28 / 7739
15
 (OMIM) Stiff skin Very frequent [Orphanet] 31 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: