Immunoglobulin A vasculitis

General Information (adopted from Orphanet):

Synonyms, Signs: Henoch-Schönlein purpura
Anaphylactoid purpura
IgA vasculitis
Purpura rheumatica
Rheumatoid purpura
Number of Symptoms 36
OrphanetNr: 761
OMIM Id:
ICD-10: D69.0
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Not applicable
[Orphanet]
Age of onset: Childhood
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Immune complex mediated vasculitis
 -Rare circulatory system disease
 -Rare systemic or rheumatologic disease
Secondary glomerular disease
 -Rare renal disease
Secondary interstitial lung disease specific to childhood associated with a systemic vasculitis
 -Rare respiratory disease

Symptom Information: Sort by abundance 

1
 (HPO:0000083) Renal insufficiency Occasional [Orphanet] 232 / 7739
2
 (HPO:0000790) Hematuria Very frequent [Orphanet] 106 / 7739
3
 (HPO:0000093) Proteinuria Occasional [Orphanet] 169 / 7739
4
 (HPO:0100796) Orchitis Frequent [Orphanet] 7 / 7739
5
 (HPO:0100820) Glomerulopathy Occasional [Orphanet] 46 / 7739
6
 (HPO:0100533) Inflammatory abnormality of the eye Occasional [Orphanet] 70 / 7739
7
 (HPO:0001250) Seizures Occasional [Orphanet] 1245 / 7739
8
 (HPO:0004374) Hemiplegia/hemiparesis Occasional [Orphanet] 158 / 7739
9
 (HPO:0002383) Encephalitis Frequent [Orphanet] 41 / 7739
10
 (HPO:0002315) Headache Frequent [Orphanet] 175 / 7739
11
 (HPO:0005059) Arthralgia/arthritis Frequent [Orphanet] 141 / 7739
12
 (HPO:0100769) Synovitis Frequent [Orphanet] 86 / 7739
13
 (HPO:0100550) Tendon rupture Frequent [Orphanet] 17 / 7739
14
 (HPO:0002017) Nausea and vomiting Very frequent [Orphanet] 134 / 7739
15
 (HPO:0002242) Abnormality of the intestine Frequent [Orphanet] 42 / 7739
16
 (HPO:0005244) Gastrointestinal infarctions Very frequent [Orphanet] 14 / 7739
17
 (HPO:0002039) Anorexia Frequent [Orphanet] 62 / 7739
18
 (HPO:0002027) Abdominal pain Very frequent [Orphanet] 184 / 7739
19
 (HPO:0002239) Gastrointestinal hemorrhage Occasional [Orphanet] 97 / 7739
20
 (HPO:0010783) Erythema Frequent [Orphanet] 138 / 7739
21
 (HPO:0011276) Vascular skin abnormality Frequent [Orphanet] 24 / 7739
22
 (HPO:0000988) Skin rash Very frequent [Orphanet] 98 / 7739
23
 (HPO:0001025) Urticaria Occasional [Orphanet] 73 / 7739
24
 (HPO:0001933) Subcutaneous hemorrhage Very frequent [Orphanet] 50 / 7739
25
 (HPO:0200042) Skin ulcer Frequent [Orphanet] 138 / 7739
26
 (HPO:0200039) Pustule Very frequent [Orphanet] 20 / 7739
27
 (HPO:0100665) Angioedema Occasional [Orphanet] 14 / 7739
28
 (HPO:0000978) Bruising susceptibility Very frequent [Orphanet] 123 / 7739
29
 (HPO:0012089) Arteritis Very frequent [Orphanet] 40 / 7739
30
 (HPO:0000969) Edema Occasional [Orphanet] 117 / 7739
31
 (HPO:0001945) Fever Frequent [Orphanet] 218 / 7739
32
 (HPO:0002091) Restrictive ventilatory defect Occasional [Orphanet] 46 / 7739
33
 (HPO:0003326) Myalgia Frequent [Orphanet] 143 / 7739
34
 (HPO:0001324) Muscle weakness Occasional [Orphanet] 859 / 7739
35
 (HPO:0012795) Abnormality of the optic disc Occasional [Orphanet] 187 / 7739
36
 (MedDRA:10025421) Macule Occasional [Orphanet] 55 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: