Tropical endomyocardial fibrosis

General Information (adopted from Orphanet):

Synonyms, Signs: TEMF
Davies disease
Number of Symptoms 21
OrphanetNr: 75565
OMIM Id:
ICD-10: I42.3
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset: All ages
23287119 [IBIS]

Disease classification (adopted from Orphanet):

Parent Diseases: Non-familial restrictive cardiomyopathy
 -Rare cardiac disease

Symptom Information: Sort by abundance 

1
 (HPO:0001217) Clubbing 23287119 IBIS 39 / 7739
2
 (HPO:0001541) Ascites 23287119 IBIS 94 / 7739
3
 (HPO:0002240) Hepatomegaly 23287119 IBIS 467 / 7739
4
 (HPO:0004395) Malnutrition 23287119 IBIS 12 / 7739
5
 (HPO:0000961) Cyanosis 23287119 IBIS 60 / 7739
6
 (HPO:0006685) Endocardial fibrosis 23287119 IBIS 9 / 7739
7
 (HPO:0011103) Abnormality of the left ventricular outflow tract 23287119 IBIS 12 / 7739
8
 (HPO:0010444) Pulmonary insufficiency 23287119 IBIS 11 / 7739
9
 (HPO:0001635) Congestive heart failure 23287119 IBIS 232 / 7739
10
 (HPO:0002092) Pulmonary hypertension 23287119 IBIS 109 / 7739
11
 (HPO:0006683) Abnormal ventricular filling 23287119 IBIS 5 / 7739
12
 (HPO:0005110) Atrial fibrillation 23287119 IBIS 71 / 7739
13
 (HPO:0001723) Restrictive cardiomyopathy 23287119 IBIS 22 / 7739
14
 (HPO:0001880) Eosinophilia 23287119 IBIS 35 / 7739
15
 (HPO:0005386) Recurrent protozoan infections 23287119 IBIS 2 / 7739
16
 (MedDRA:10047240) Venous pressure jugular increased 23287119 IBIS 6 / 7739
17
 (MedDRA:10067286) Left atrial dilatation 23287119 IBIS 10 / 7739
18
 (MedDRA:10067282) Right atrial dilatation 23287119 IBIS 8 / 7739
19
 (MedDRA:10061201) Helminthic infection 23287119 IBIS 1 / 7739
20
 (HPO:0030148) Heart murmur 23287119 IBIS 29 / 7739
21
 (MedDRA:10007978) Central venous pressure abnormal 23287119 IBIS 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: