Rh deficiency syndrome

General Information (adopted from Orphanet):

Synonyms, Signs: RH-NULL DISEASE, INCLUDED
RHN RH DEFICIENCY SYNDROME, INCLUDED
Rh-null syndrome
Number of Symptoms 11
OrphanetNr: 71275
OMIM Id: 268150
ICD-10: D58.8
UMLs: C0272052
MeSH:
MedDRA:
Snomed: 37272000

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal recessive
[Orphanet]
Age of onset: No data available
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Stomatocytosis
 -Rare genetic disease
 -Rare hematologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0000952) Jaundice 105 / 7739
2
 (HPO:0004446) Stomatocytosis 11 / 7739
3
 (HPO:0005502) Increased red cell osmotic fragility 5 / 7739
4
 (HPO:0001878) Hemolytic anemia 83 / 7739
5
 (HPO:0008282) Unconjugated hyperbilirubinemia 9 / 7739
6
 (OMIM) No red cell Rh blood group antigens 1 / 7739
7
 (OMIM) Shortened red cell survival 1 / 7739
8
 (HPO:0000007) Autosomal recessive inheritance 2538 / 7739
9
 (OMIM) Weak reaction with anti-U and anti-S 1 / 7739
10
 (OMIM) Rh-null 1 / 7739
11
 (OMIM) Increased fetal hemoglobin 5 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: