Intrahepatic cholestasis of pregnancy
General Information (adopted from Orphanet):
| Synonyms, Signs: |
Recurrent intrahepatic cholestasis of pregnancy Pregnancy-related cholestasis Gravidic intrahepatic cholestasis |
| Number of Symptoms | 6 |
| OrphanetNr: | 69665 |
| OMIM Id: |
147480
614972 |
| ICD-10: |
O26.6 |
| UMLs: |
|
| MeSH: |
C535932 |
| MedDRA: |
|
| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
Multifactorial Not applicable [Orphanet] |
| Age of onset: |
Adult [Orphanet] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Rare disorder related with pregnancy, childbirth and puerperium
-Rare gynecologic or obstetric disease Rare parenchymatous liver disease -Rare hepatic disease |
Symptom Information:
|
|
(HPO:0001622) | Premature birth | 100 / 7739 | ||||
|
|
(HPO:0200148) | Abnormal liver function tests during pregnancy | 3 / 7739 | ||||
|
|
(HPO:0001406) | Intrahepatic cholestasis | 16 / 7739 | ||||
|
|
(HPO:0000989) | Pruritus | 111 / 7739 | ||||
|
|
(HPO:0200150) | Increased serum bile acid concentration during pregnancy | 2 / 7739 | ||||
|
|
(HPO:0000006) | Autosomal dominant inheritance | 2518 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
|---|