Nephroblastoma

General Information (adopted from Orphanet):

Synonyms, Signs: Renal embryonic tumor
Wilms tumor
Number of Symptoms 15
OrphanetNr: 654
OMIM Id: 194070
194071
194090
601363
601583
ICD-10: C64
UMLs: C0027708
MeSH: D009396
MedDRA: 10029145
Snomed: 25081006
302849000

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant
Not applicable
[Orphanet]
Age of onset: Childhood
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Genetic renal tumor
 -Rare genetic disease

Symptom Information: Sort by abundance 

1
 (HPO:0000790) Hematuria Occasional [Orphanet] 106 / 7739
2
 (HPO:0002667) Nephroblastoma 30 / 7739
3
 (HPO:0009726) Renal neoplasm Very frequent [Orphanet] 20 / 7739
4
 (HPO:0008053) Aplasia/Hypoplasia of the iris Occasional [Orphanet] 38 / 7739
5
 (HPO:0002027) Abdominal pain Very frequent [Orphanet] 184 / 7739
6
 (HPO:0002896) Neoplasm of the liver Occasional [Orphanet] 17 / 7739
7
 (HPO:0004325) Decreased body weight Occasional [Orphanet] 492 / 7739
8
 (HPO:0000822) Hypertension Occasional [Orphanet] 224 / 7739
9
 (HPO:0001945) Fever Occasional [Orphanet] 218 / 7739
10
 (HPO:0100526) Neoplasm of the lung Occasional [Orphanet] 26 / 7739
11
 (HPO:0002664) Neoplasm Very frequent [Orphanet] 111 / 7739
12
 (HPO:0002716) Lymphadenopathy Occasional [Orphanet] 129 / 7739
13
 (HPO:0001428) Somatic mutation 100 / 7739
14
 (HPO:0001425) Heterogeneous 132 / 7739
15
 (HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: