Cirrhotic cardiomyopathy
General Information (adopted from Orphanet):
| Synonyms, Signs: |
|
| Number of Symptoms | 25 |
| OrphanetNr: | 57777 |
| OMIM Id: |
|
| ICD-10: |
I42.8 |
| UMLs: |
|
| MeSH: |
|
| MedDRA: |
|
| Snomed: |
|
Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
|
| Age of onset: |
|
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Non-familial dilated cardiomyopathy
-Rare cardiac disease Non-familial hypertrophic cardiomyopathy -Rare cardiac disease Rare parenchymatous liver disease -Rare hepatic disease |
Comment:
| Cirrhotic cardiomyopathy has been defined as a chronic cardiac dysfunction in patients with cirrhosis characterized by impaired contractile responsiveness to stress and/or altered diastolic relaxation with electrophysiological abnormalities in the absence of other known cardiac disease (PMID:26755864). |
Symptom Information:
|
|
(HPO:0000083) | Renal insufficiency | 26556983 | IBIS | 232 / 7739 | ||
|
|
(HPO:0011733) | Abnormality of adrenal physiology | 26556983 | IBIS | 1 / 7739 | ||
|
|
(HPO:0001541) | Ascites | 26556983 | IBIS | 94 / 7739 | ||
|
|
(HPO:0001409) | Portal hypertension | 26556983 | IBIS | 39 / 7739 | ||
|
|
(HPO:0001399) | Hepatic failure | 26556983 | IBIS | 80 / 7739 | ||
|
|
(HPO:0001394) | Cirrhosis | 26556983 | IBIS | 102 / 7739 | ||
|
|
(HPO:0001639) | Hypertrophic cardiomyopathy | 26556983 | IBIS | 137 / 7739 | ||
|
|
(HPO:0011028) | Abnormality of blood circulation | 26556983 | IBIS | 2 / 7739 | ||
|
|
(HPO:0005120) | Abnormality of cardiac atrium | 26556983 | IBIS | 5 / 7739 | ||
|
|
(HPO:0005162) | Left ventricular failure | 26556983 | IBIS | 18 / 7739 | ||
|
|
(HPO:0006670) | Impaired myocardial contractility | 26556983 | IBIS | 9 / 7739 | ||
|
|
(HPO:0001626) | Abnormality of the cardiovascular system | 26556983 | IBIS | 73 / 7739 | ||
|
|
(HPO:0001640) | Cardiomegaly | 26556983 | IBIS | 81 / 7739 | ||
|
|
(HPO:0012665) | Moderately reduced ejection fraction | 26556983 | IBIS | 4 / 7739 | ||
|
|
(HPO:0001657) | Prolonged QT interval | 26556983 | IBIS | 33 / 7739 | ||
|
|
(HPO:0006673) | Reduced systolic function | 26556983 | IBIS | 11 / 7739 | ||
|
|
(HPO:0001635) | Congestive heart failure | 26556983 | IBIS | 232 / 7739 | ||
|
|
(HPO:0011106) | Hypovolemia | 26556983 | IBIS | 1 / 7739 | ||
|
|
(MedDRA:10007596) | Cardiac output increased | 26556983 | IBIS | 1 / 7739 | ||
|
|
(MedDRA:10029752) | Norepinephrine increased | 26556983 | IBIS | 1 / 7739 | ||
|
|
(MedDRA:10068627) | Chronotropic incompetence | 26556983 | IBIS | 2 / 7739 | ||
|
|
(MedDRA:10052337) | Diastolic dysfunction | 26556983 | IBIS | 14 / 7739 | ||
|
|
(MedDRA:10007548) | Cardiac enzymes increased | 26556983 | IBIS | 4 / 7739 | ||
|
|
(MedDRA:10007595) | Cardiac output decreased | 26556983 | IBIS | 3 / 7739 | ||
|
|
(MedDRA:10049671) | Negative cardiac inotropic effect | 26556983 | IBIS | 1 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
|---|