Adamantinoma

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 23
OrphanetNr: 55881
OMIM Id: 102660
ICD-10:
UMLs: C1367554
MeSH: D050398
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: 0.11 of 100 000 [Orphanet]
Inheritance: Not applicable
[Orphanet]
Age of onset: Childhood
Adolescent
Adult
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Genetic bone tumor
 -Rare genetic disease
Rare bone tumor
 -Rare bone disease
 -Rare oncologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0012062) Bone cyst Occasional [Orphanet] 19 / 7739
2
 (HPO:0000940) Abnormal diaphysis morphology Very frequent [Orphanet] 41 / 7739
3
 (HPO:0002653) Bone pain Very frequent [Orphanet] 75 / 7739
4
 (HPO:0003103) Abnormal cortical bone morphology Very frequent [Orphanet] 38 / 7739
5
 (HPO:0002797) Osteolysis Very frequent [Orphanet] 68 / 7739
6
 (HPO:0002992) Abnormality of the tibia Very frequent [Orphanet] 51 / 7739
7
 (HPO:0011867) Abnormality of the wing of the ilium Occasional [Orphanet] 123 / 7739
8
 (HPO:0010622) Neoplasm of the skeletal system Very frequent [Orphanet] 30 / 7739
9
 (HPO:0003063) Abnormality of the humerus Occasional [Orphanet] 36 / 7739
10
 (HPO:0002991) Abnormality of the fibula Occasional [Orphanet] 49 / 7739
11
 (HPO:0000772) Abnormality of the ribs Occasional [Orphanet] 146 / 7739
12
 (HPO:0003468) Abnormality of the vertebrae Occasional [Orphanet] 77 / 7739
13
 (HPO:0002659) Increased susceptibility to fractures Frequent [Orphanet] 110 / 7739
14
 (HPO:0002823) Abnormality of the femur Occasional [Orphanet] 61 / 7739
15
 (HPO:0002818) Abnormality of the radius Occasional [Orphanet] 96 / 7739
16
 (HPO:0011001) Increased bone mineral density Very frequent [Orphanet] 78 / 7739
17
 (HPO:0002896) Neoplasm of the liver Occasional [Orphanet] 17 / 7739
18
 (HPO:0100526) Neoplasm of the lung Frequent [Orphanet] 26 / 7739
19
 (HPO:0002664) Neoplasm 111 / 7739
20
 (HPO:0002716) Lymphadenopathy Occasional [Orphanet] 129 / 7739
21
 (OMIM) Adamantinoma of long bones 1 / 7739
22
 (HPO:0030448) Soft tissue sarcoma Frequent [Orphanet] 18 / 7739
23
 (HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: