Mantle cell lymphoma
General Information (adopted from Orphanet):
| Synonyms, Signs: |
MCL LCM Mantle zone lymphoma |
| Number of Symptoms | 7 |
| OrphanetNr: | 52416 |
| OMIM Id: |
|
| ICD-10: |
C83.1 |
| UMLs: |
|
| MeSH: |
D020522 |
| MedDRA: |
10061275 |
| Snomed: |
443487006 74654000 |
Prevalence, inheritance and age of onset:
| Prevalence: | 4 of 100 000 [Orphanet] |
| Inheritance: |
Multifactorial Not applicable [Orphanet] |
| Age of onset: |
Adult [Orphanet] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Aggressive B-cell non-Hodgkin lymphoma
-Rare hematologic disease -Rare oncologic disease |
Symptom Information:
|
|
(HPO:0002039) | Anorexia | Frequent [Orphanet] | 62 / 7739 | |||
|
|
(HPO:0001744) | Splenomegaly | Frequent [Orphanet] | 337 / 7739 | |||
|
|
(HPO:0004325) | Decreased body weight | Frequent [Orphanet] | 492 / 7739 | |||
|
|
(HPO:0012145) | Abnormality of multiple cell lineages in the bone marrow | Frequent [Orphanet] | 11 / 7739 | |||
|
|
(HPO:0004377) | Hematological neoplasm | Very frequent [Orphanet] | 12 / 7739 | |||
|
|
(HPO:0002716) | Lymphadenopathy | Very frequent [Orphanet] | 129 / 7739 | |||
|
|
(HPO:0001324) | Muscle weakness | Frequent [Orphanet] | 859 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
|---|