Vogt-Koyanagi-Harada disease
General Information (adopted from Orphanet):
| Synonyms, Signs: |
Uveomenigitic syndrome |
| Number of Symptoms | 13 |
| OrphanetNr: | 3437 |
| OMIM Id: |
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| ICD-10: |
H20.8 H30.8 |
| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
193497004 |
Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
Multifactorial [Orphanet] |
| Age of onset: |
All ages [Orphanet] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Eyebrow/eyelashes pigmentation anomaly
-Rare eye disease -Rare genetic disease Panuveitis -Rare eye disease Rare neuroinflammatory or neuroimmunological disease -Rare neurologic disease |
Symptom Information:
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(HPO:0100840) | Aplasia/Hypoplasia of the eyebrow | Very frequent [Orphanet] | 117 / 7739 | |||
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(HPO:0200102) | Sparse or absent eyelashes | Very frequent [Orphanet] | 64 / 7739 | |||
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(HPO:0000572) | Visual loss | Frequent [Orphanet] | 272 / 7739 | |||
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(HPO:0000505) | Visual impairment | Very frequent [Orphanet] | 297 / 7739 | |||
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(HPO:0000501) | Glaucoma | Frequent [Orphanet] | 180 / 7739 | |||
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(HPO:0000518) | Cataract | Frequent [Orphanet] | 454 / 7739 | |||
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(HPO:0000541) | Retinal detachment | Frequent [Orphanet] | 87 / 7739 | |||
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(HPO:0000407) | Sensorineural hearing impairment | Very frequent [Orphanet] | 524 / 7739 | |||
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(HPO:0004322) | Short stature | Frequent [Orphanet] | 1232 / 7739 | |||
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(HPO:0001006) | Hypotrichosis | Very frequent [Orphanet] | 219 / 7739 | |||
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(HPO:0001053) | Hypopigmented skin patches | Very frequent [Orphanet] | 80 / 7739 | |||
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(HPO:0002216) | Premature graying of hair | Very frequent [Orphanet] | 43 / 7739 | |||
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(HPO:0012758) | Neurodevelopmental delay | Very frequent [Orphanet] | 949 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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