Nodular non-suppurative panniculitis

General Information (adopted from Orphanet):

Synonyms, Signs: WCD
Idiopathic lobular panniculitis
Idiopathic nodular panniculitis
Weber-Christian disease
Relapsing febrile nodular panniculitis
Relapsing febrile nodular nonsuppurative panniculitis
Pfeiffer-Weber-Christian syndrome
Weber-Christian panniculitis
Number of Symptoms 15
OrphanetNr: 33577
OMIM Id:
ICD-10: M35.6
UMLs: C0030328
MeSH: D010201
MedDRA: 10047883
Snomed: 33760009

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Not applicable
[Orphanet]
Age of onset: Adult
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Subcutaneous tissue disease
 -Rare skin disease

Symptom Information: Sort by abundance 

1
 (HPO:0100533) Inflammatory abnormality of the eye Occasional [Orphanet] 70 / 7739
2
 (HPO:0005059) Arthralgia/arthritis Very frequent [Orphanet] 141 / 7739
3
 (HPO:0002027) Abdominal pain Very frequent [Orphanet] 184 / 7739
4
 (HPO:0002017) Nausea and vomiting Very frequent [Orphanet] 134 / 7739
5
 (HPO:0002240) Hepatomegaly Occasional [Orphanet] 467 / 7739
6
 (HPO:0001744) Splenomegaly Occasional [Orphanet] 337 / 7739
7
 (HPO:0004325) Decreased body weight Very frequent [Orphanet] 492 / 7739
8
 (HPO:0001031) Subcutaneous lipoma Very frequent [Orphanet] 112 / 7739
9
 (HPO:0008065) Aplasia/Hypoplasia of the skin Very frequent [Orphanet] 81 / 7739
10
 (HPO:0010783) Erythema Very frequent [Orphanet] 138 / 7739
11
 (HPO:0001945) Fever Very frequent [Orphanet] 218 / 7739
12
 (HPO:0000969) Edema Very frequent [Orphanet] 117 / 7739
13
 (HPO:0002960) Autoimmunity Occasional [Orphanet] 78 / 7739
14
 (HPO:0003326) Myalgia Very frequent [Orphanet] 143 / 7739
15
 (HPO:0003549) Abnormality of connective tissue Very frequent [Orphanet] 22 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: