Congenital fibrinogen deficiency

General Information (adopted from Orphanet):

Synonyms, Signs: HYPODYSFIBRINOGENEMIA, CONGENITAL, INCLUDED
DYSFIBRINOGENEMIA, CONGENITAL, INCLUDED
Number of Symptoms 6
OrphanetNr: 335
OMIM Id: 202400
ICD-10: D68.2
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: 0.15 of 100 000 [Orphanet]
Inheritance: Autosomal dominant
Autosomal recessive
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Rare hemorrhagic disorder due to a constitutional coagulation factors defect
 -Rare genetic disease
 -Rare hematologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0012223) Splenic rupture 6 / 7739
2
 (OMIM) Osseous hemorrhage 5 / 7739
3
 (OMIM) Blood completely incoagulable 5 / 7739
4
 (OMIM) Afibrinogenemia 5 / 7739
5
 (OMIM) Hepatic hemorrhage 5 / 7739
6
 (OMIM) Bleeding mild to severe 5 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: