Multifocal atrial tachycardia
General Information (adopted from Orphanet):
| Synonyms, Signs: |
MAT Chaotic atrial tachycardia |
| Number of Symptoms | 21 |
| OrphanetNr: | 3282 |
| OMIM Id: |
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| ICD-10: |
I47.1 |
| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
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| Age of onset: |
Neonatal Infancy 11499730 [IBIS] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Non-genetic cardiac rhythm disease
-Rare cardiac disease |
Comment:
| Multifocal atrial tachycardia (MAT) is a rare supraventricular arrhythmia in infants and children, accounting for approximately 1% of supraventricular tachycardia substrates (PMID:23618974). |
Symptom Information:
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(HPO:0001627) | Abnormal heart morphology | Frequent [IBIS] | 47% (n=15) | 11499730 | IBIS | 19 / 7739 |
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(HPO:0001713) | Abnormality of cardiac ventricle | Occasional [IBIS] | 27% (n=15) | 11499730 | IBIS | 4 / 7739 |
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(HPO:0011675) | Arrhythmia | 11499730 | IBIS | 226 / 7739 | ||
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(HPO:0011701) | Multifocal atrial tachycardia | Very frequent [IBIS] | 23618974 | IBIS | 7 / 7739 | |
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(HPO:0002094) | Dyspnea | 17051756 | IBIS | 132 / 7739 | ||
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(HPO:0004755) | Supraventricular tachycardia | 17051756 | IBIS | 20 / 7739 | ||
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(HPO:0001635) | Congestive heart failure | 17051756 | IBIS | 232 / 7739 | ||
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(HPO:0001631) | Atria septal defect | 17051756 | IBIS | 274 / 7739 | ||
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(HPO:0001629) | Ventricular septal defect | 17051756 | IBIS | 316 / 7739 | ||
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(HPO:0001680) | Coarctation of aorta | 17051756 | IBIS | 57 / 7739 | ||
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(HPO:0001643) | Patent ductus arteriosus | 17051756 | IBIS | 228 / 7739 | ||
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(HPO:0001719) | Double outlet right ventricle | 17051756 | IBIS | 12 / 7739 | ||
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(HPO:0030680) | Abnormality of cardiovascular system morphology | 17051756 | IBIS | 355 / 7739 | ||
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(HPO:0002878) | Respiratory failure | 17051756 | IBIS | 57 / 7739 | ||
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(MedDRA:10050384) | Electrocardiogram P wave abnormal | 21267831 | IBIS | 1 / 7739 | ||
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(HPO:0001640) | Cardiomegaly | 21267831 | IBIS | 81 / 7739 | ||
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(HPO:0002240) | Hepatomegaly | 21267831 | IBIS | 467 / 7739 | ||
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(HPO:0002615) | Hypotension | 21267831 | IBIS | 52 / 7739 | ||
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(HPO:0002789) | Tachypnea | 21267831 | IBIS | 48 / 7739 | ||
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(HPO:0002098) | Respiratory distress | 21267831 | IBIS | 75 / 7739 | ||
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(HPO:0001962) | Palpitations | 23618974 | IBIS | 62 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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