Synovial sarcoma

General Information (adopted from Orphanet):

Synonyms, Signs: Synovialosarcoma
Number of Symptoms 2
OrphanetNr: 3273
OMIM Id: 300813
ICD-10: C49.9
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Not applicable
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Soft tissue sarcoma
 -Rare oncologic disease

Symptom Information: Sort by abundance 

1
(HPO:0012570) Synovial sarcoma 1 / 7739
2
(HPO:0001428) Somatic mutation 100 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Synovial sarcomas, which represent approximately 10% of all soft tissue sarcomas, are aggressive spindle cell sarcomas containing in some cases areas of epithelial differentiation. They consistently show a specific t(X;18)(p11.2;q11.2), which usually represents either of 2 gene fusions, ...
Clinical Description OMIM The patient described by Griffin and Emanuel (1987) was a 12-year-old black female with an unremarkable previous medical history, who presented with a 3-month history of right calf pain and swelling following a fall onto the right leg. ...