Lymphoid hypereosinophilic syndrome

General Information (adopted from Orphanet):

Synonyms, Signs: HES-L
Lymphoid HES
Number of Symptoms 10
OrphanetNr: 314970
OMIM Id:
ICD-10: D47.5
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: Secondary hypereosinophilic syndrome
 -Rare cardiac disease
 -Rare hematologic disease
 -Rare oncologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0012393) Allergy 19630574 IBIS 3 / 7739
2
 (HPO:0002665) Lymphoma 19630574 IBIS 60 / 7739
3
 (HPO:0011974) Myelofibrosis Rare [IBIS] 19630574 IBIS 6 / 7739
4
 (HPO:0006685) Endocardial fibrosis Rare [IBIS] 19630574 IBIS 9 / 7739
5
 (HPO:0006536) Obstructive lung disease Frequent [IBIS] 19630574 IBIS 7 / 7739
6
 (HPO:0002012) Abnormality of the abdominal organs Frequent [IBIS] 19630574 IBIS 2 / 7739
7
 (HPO:0001005) Dermatological manifestations of systemic disorders Frequent [IBIS] 19630574 IBIS 1 / 7739
8
 (HPO:0003212) Increased IgE level 19630574 IBIS 13 / 7739
9
 (HPO:0011113) Abnormality of cytokine secretion 19630574 IBIS 1 / 7739
10
 (HPO:0001880) Eosinophilia Very frequent [IBIS] 19630574 IBIS 35 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference
PDGFRA rs121908587 pathogenic RCV000014509.25

Additional Information: