Familial isolated pituitary adenoma

General Information (adopted from Orphanet):

Synonyms, Signs: FIPA
Number of Symptoms 14
OrphanetNr: 314777
OMIM Id: 102200
600634
ICD-10: D35.2
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant
[Orphanet]
Age of onset: All ages
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Pituitary adenoma
 -Rare endocrine disease
 -Rare genetic disease
 -Rare oncologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0000858) Menstrual irregularities 42 / 7739
2
 (HPO:0000280) Coarse facial features 189 / 7739
3
 (HPO:0100829) Galactorrhea 7 / 7739
4
 (HPO:0006767) Pituitary prolactin cell adenoma 3 / 7739
5
 (HPO:0002893) Pituitary adenoma 16 / 7739
6
 (HPO:0000870) Prolactin excess 10 / 7739
7
 (HPO:0000845) Growth hormone excess 18 / 7739
8
 (HPO:0011760) Pituitary growth hormone cell adenoma 1 / 7739
9
 (HPO:0000822) Hypertension 224 / 7739
10
 (HPO:0001638) Cardiomyopathy 192 / 7739
11
 (HPO:0001712) Left ventricular hypertrophy 76 / 7739
12
 (HPO:0001428) Somatic mutation 100 / 7739
13
 (HPO:0030269) Increased serum insulin-like growth factor 1 {comment="HPO:probinson"} 2 / 7739
14
 (HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: