Petty et al. (1990) described what they considered to be a newly recognized form of congenital progeroid syndrome in a 5-year-old girl. They suggested that the 46-year-old woman reported by Wiedemann (1979) had the same syndrome. Common manifestations ... Petty et al. (1990) described what they considered to be a newly recognized form of congenital progeroid syndrome in a 5-year-old girl. They suggested that the 46-year-old woman reported by Wiedemann (1979) had the same syndrome. Common manifestations included pre- and postnatal growth retardation, markedly diminished subcutaneous fat, wrinkled skin, abnormally scant hair growth, hypoplastic distal phalanges with hypoplastic nails, umbilical hernia, large open anterior fontanel, and normal cognitive and motor development. Both patients had a prematurely aged appearance since birth. Petty et al. (1990) noted that patients with Wiedemann-Rautenstrauch syndrome (WRS; 264090) show similarities to their patient, but differ by the presence of natal teeth, large hands and feet with long, tapering digits, developmental delay, and neurologic impairment.