Camptodactyly of fingers

General Information (adopted from Orphanet):

Synonyms, Signs: CAMPD1
CAMPTODACTYLY AND KNUCKLE PADS STREBLODACTYLY, INCLUDED
Number of Symptoms 7
OrphanetNr: 295016
OMIM Id: 114200
ICD-10: Q68.1
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: Congenital deformities of fingers
 -Rare developmental defect during embryogenesis

Symptom Information: Sort by abundance 

1
(HPO:0003166) Increased urinary taurine 5 / 7739
2
(HPO:0100490) Camptodactyly of finger 212 / 7739
3
(HPO:0004976) Knee dislocation 6 / 7739
4
(HPO:0012385) Camptodactyly 113 / 7739
5
(OMIM) Knee-joint subluxation 1 / 7739
6
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
7
(OMIM) Associated taurinuria 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Camptodactyly is defined as a permanent flexion contrature of 1 or both fifth fingers at the proximal interphalangeal joints. Additional fingers might be affected, but the little finger is always involved. Usually the condition appears to be sporadic ...
Clinical Description OMIM In a rural area of western North Carolina, Murphy (1926) described camptodactyly in many members of 5 generations. Eleven of the affected persons also had knee-joint subluxation which was usually easily reduced.

Hefner (1929, 1941) reported ...