Idiopathic recurrent pericarditis

General Information (adopted from Orphanet):

Synonyms, Signs: Idiopathic relapsing pericarditis
Number of Symptoms 13
OrphanetNr: 251307
OMIM Id:
ICD-10: E85.0
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Sporadic
23052671 [IBIS]
Age of onset: Childhood
Adult
23052671 [IBIS]

Disease classification (adopted from Orphanet):

Parent Diseases: Unclassified autoinflammatory syndrome
 -Rare systemic or rheumatologic disease

Comment:

Idiopathic recurrent pericarditis is viewed as an autoinflammatory or autoimmune disease. It is defined by 2 or more episodes of acute pericarditis of unknown etiology (PMID:23711245).

Symptom Information: Sort by abundance 

1
 (HPO:0003565) Elevated erythrocyte sedimentation rate Frequent [IBIS] 19116906 IBIS 31 / 7739
2
 (HPO:0003116) Abnormal echocardiogram Frequent [IBIS] 23052671 IBIS 33 / 7739
3
 (HPO:0001649) Tachycardia 23052671 IBIS 53 / 7739
4
 (HPO:0012764) Orthopnea 23052671 IBIS 9 / 7739
5
 (HPO:0002094) Dyspnea 23052671 IBIS 132 / 7739
6
 (HPO:0003493) Antinuclear antibody positivity 18674829 IBIS 15 / 7739
7
 (HPO:0001974) Leukocytosis Frequent [IBIS] 25165036 IBIS 33 / 7739
8
 (HPO:0030148) Heart murmur Frequent [IBIS] 25165036 IBIS 29 / 7739
9
 (HPO:0011227) Elevated C-reactive protein level Frequent [IBIS] 25165036 IBIS 55 / 7739
10
 (HPO:0001698) Pericardial effusion Frequent [IBIS] 25165036 IBIS 20 / 7739
11
 (HPO:0001954) Episodic fever Frequent [IBIS] 25165036 IBIS 27 / 7739
12
 (HPO:0001701) Pericarditis Very frequent [IBIS] 25165036 IBIS 13 / 7739
13
 (HPO:0100749) Chest pain Very frequent [IBIS] 26942035 IBIS 92 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: