Erythema palmaris hereditarium

General Information (adopted from Orphanet):

Synonyms, Signs: Lane disease
Red palms disease
Number of Symptoms 3
OrphanetNr: 231031
OMIM Id: 133000
ICD-10: L59.8
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant
[Orphanet]
Age of onset: Neonatal
Infancy
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Unclassified genetic skin disease
 -Rare genetic disease
 -Rare skin disease

Symptom Information: Sort by abundance 

1
(HPO:0010783) Erythema 138 / 7739
2
(MedDRA:10033551) Palmar erythema 2 / 7739
3
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Erythema palmare hereditarium is a benign condition that was first described by Lane (1929). Erythema usually presents at birth and remains stable throughout life. Histology shows dilated vessels in the entire dermis with inflammatory infiltrate. Capillaroscopy reveals an ...
Clinical Description OMIM Sarma and Wang (2007) described a 44-year-old Chinese man, his mother, and his 7-year-old daughter who had red hands since birth. The condition was asymptomatic. There was no hyperhidrosis, hyperkeratosis, or any scaling. No erythema was noted on ...