Ledderhose disease
General Information (adopted from Orphanet):
| Synonyms, Signs: |
Plantar fibromatosis |
| Number of Symptoms | 6 |
| OrphanetNr: | 199251 |
| OMIM Id: |
|
| ICD-10: |
M72.2 |
| UMLs: |
C0158360 |
| MeSH: |
C537000 |
| MedDRA: |
10035154 |
| Snomed: |
13370002 |
Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
|
| Age of onset: |
Adult [Orphanet] |
Disease classification (adopted from Orphanet):
| Parent Diseases: |
Superficial fibromatosis
-Rare oncologic disease -Rare skin disease |
Symptom Information:
|
|
(HPO:0000763) | Sensory neuropathy | Very frequent [Orphanet] | 78 / 7739 | |||
|
|
(HPO:0009830) | Peripheral neuropathy | Occasional [Orphanet] | 206 / 7739 | |||
|
|
(HPO:0005059) | Arthralgia/arthritis | Very frequent [Orphanet] | 141 / 7739 | |||
|
|
(HPO:0001031) | Subcutaneous lipoma | Frequent [Orphanet] | 112 / 7739 | |||
|
|
(HPO:0100679) | Lack of skin elasticity | Very frequent [Orphanet] | 29 / 7739 | |||
|
|
(OMIM) | Stiff skin | Very frequent [Orphanet] | 31 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
|---|