Absence of the breasts and nipples may occur as an isolated anomaly or as part of a syndrome. Hypoplasia or aplasia of the breasts and nipples occurs in anhidrotic ectodermal dysplasia (305100). Absence of the breast also occurs ... Absence of the breasts and nipples may occur as an isolated anomaly or as part of a syndrome. Hypoplasia or aplasia of the breasts and nipples occurs in anhidrotic ectodermal dysplasia (305100). Absence of the breast also occurs with Poland syndrome (173800).
Goldenring and Crelin (1961) described absence of breast and nipples in a mother and daughter, as did Trier (1965).
Greenberg (1987) described an infant girl with athelia (absence of the nipples) and choanal atresia, born to ... Goldenring and Crelin (1961) described absence of breast and nipples in a mother and daughter, as did Trier (1965). Greenberg (1987) described an infant girl with athelia (absence of the nipples) and choanal atresia, born to a woman treated for hyperthyroidism throughout pregnancy with methimazole and propranolol. The possibility of methimazole teratogenicity was raised. Papadimitriou et al. (2009) reported a 13.5-year-old Greek girl, born of nonconsanguineous parents, who had bilateral amazia (absence of the mammary glands), hypoplastic areolae, and normal nipple formation. In addition, bilateral choanal atresia had been detected soon after birth and surgically corrected. Physical examination of the patient was otherwise unremarkable, and renal ultrasonography and chest radiography were normal.