Hypereosinophilic syndrome

General Information (adopted from Orphanet):

Synonyms, Signs:
Number of Symptoms 0
OrphanetNr: 168956
OMIM Id:
ICD-10: D47.5
UMLs: C1540912
MeSH: D017681
MedDRA: 10048643
Snomed: 128835008

Prevalence, inheritance and age of onset:

Prevalence: > 3 of 100 000 [IBIS]
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: Myeloproliferative neoplasm
 -Rare hematologic disease
 -Rare oncologic disease
Non-familial restrictive cardiomyopathy
 -Rare cardiac disease

Comment:

This term does not characterize a disease but a group of diseases. Annotations can be found at a more specific level (Primary hypereosinophilic syndrome, econdary hypereosinophilic syndrome, Lymphoid hypereosinophilic syndrome, Idiopathic hypereosinophilic syndrome). The prevalence is unknown varying between 0.36 and 6.3 per 100 000 (PMID:20639012)

Symptom Information: Sort by abundance 

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference
PDGFRA rs121908587 pathogenic RCV000014509.25

Additional Information: