MORBID OBESITY AND SPERMATOGENIC FAILURE
General Information (adopted from Orphanet):
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Synonyms, Signs:
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Number of Symptoms
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17
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OrphanetNr:
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OMIM Id:
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615703
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ICD-10:
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UMLs:
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MeSH:
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MedDRA:
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Snomed:
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Prevalence, inheritance and age of onset:
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Prevalence:
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No data available.
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Inheritance:
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Age of onset:
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Disease classification (adopted from Orphanet):
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Parent Diseases:
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No data available.
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1
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(HPO:0000789)
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Infertility |
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74 / 7739
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2
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(HPO:0000798)
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Oligospermia |
6/6 [HPO:probinson]
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13 / 7739
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3
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(HPO:0000027)
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Azoospermia |
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28 / 7739
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4
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(HPO:0001249)
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Intellectual disability |
3/11 [HPO:probinson]
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1089 / 7739
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5
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(HPO:0005978)
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Type II diabetes mellitus |
3/11 [HPO:probinson]
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68 / 7739
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6
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(HPO:0001397)
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Hepatic steatosis |
11/11 [HPO:probinson]
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75 / 7739
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7
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(HPO:0001513)
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Obesity |
10/11 [HPO:probinson]
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172 / 7739
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8
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(HPO:0001658)
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Myocardial infarction |
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30 / 7739
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9
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(HPO:0000822)
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Hypertension |
11/11 [HPO:probinson]
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224 / 7739
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10
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(HPO:0005181)
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Premature coronary artery disease |
5/15 [HPO:probinson]
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5 / 7739
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11
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(HPO:0001635)
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Congestive heart failure |
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232 / 7739
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12
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(HPO:0000855)
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Insulin resistance |
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32 / 7739
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13
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(HPO:0002155)
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Hypertriglyceridemia |
4/11 [HPO:probinson]
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67 / 7739
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14
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(HPO:0003233)
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Hypoalphalipoproteinemia |
6/11 [HPO:probinson]
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18 / 7739
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15
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(HPO:0003124)
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Hypercholesterolemia |
4/11 [HPO:probinson]
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53 / 7739
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16
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(HPO:0003141)
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Hyperbetalipoproteinemia |
2/11 [HPO:probinson]
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10 / 7739
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17
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(HPO:0000007)
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Autosomal recessive inheritance |
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2538 / 7739
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ClinVar (via SNiPA)
| Gene symbol |
Variation |
Clinical significance |
Reference |