PREGNANCY LOSS, RECURRENT, SUSCEPTIBILITY TO, 1

General Information (adopted from Orphanet):

Synonyms, Signs: STILLBIRTH, RECURRENT
EMBRYONIC LOSS, RECURRENT
FETAL LOSS, RECURRENT, SUSCEPTIBILITY TO
MISCARRIAGE, RECURRENT
RPRGL1
ABORTION, SPONTANEOUS, RECURRENT
RPRGL
RPL
Number of Symptoms 3
OrphanetNr:
OMIM Id: 614389
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0200067) Recurrent spontaneous abortion 6 / 7739
2
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
3
(OMIM) Fetal loss after 20 weeks or more of gestation 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Miscarriage, the commonest complication of pregnancy, is the spontaneous loss of a pregnancy before the fetus has reached viability. The term therefore includes all pregnancy losses from the time of conception until 24 weeks of gestation. Recurrent miscarriage, ...
Molecular genetics OMIM Majerus (1994) noted that an estimated 2 to 4% of the Dutch population and 7% of the Swedish population carried a mutant R506Q allele of coagulation factor V, the 'factor V Leiden' variant (612309.0001). The high frequency of ...