SCHIZOPHRENIA 15

General Information (adopted from Orphanet):

Synonyms, Signs: SCZD15
SCHIZOPHRENIA SUSCEPTIBILITY LOCUS, CHROMOSOME 22q13-RELATED
Number of Symptoms 2
OrphanetNr:
OMIM Id: 613950
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Polygenic inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0100753) Schizophrenia 20 / 7739
2
(HPO:0010982) Polygenic inheritance 14 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM Gauthier et al. (2010) identified a family in which a proband and 2 affected brothers had schizophrenia. The proband was of European ancestry and had a diagnosis of schizoaffective disorder at age 19. He suffered from borderline mental ...
Molecular genetics OMIM In 3 brothers with schizophrenia, Gauthier et al. (2010) identified an R1117X mutation in the SHANK3 gene (606230.0002). The parents were unaffected and did not carry the mutation, which appeared to be inherited from the paternal strand through ...