Wali et al. (2007) reported a consanguineous Pakistani family with autosomal recessive mental retardation associated with generalized alopecia. Affected individuals had complete absence of scalp hair at birth and showed lack of eyebrows, eyelashes, and axillary and pubic ... Wali et al. (2007) reported a consanguineous Pakistani family with autosomal recessive mental retardation associated with generalized alopecia. Affected individuals had complete absence of scalp hair at birth and showed lack of eyebrows, eyelashes, and axillary and pubic hair. Teeth, nails, sweating, and hearing were normal. All affected individuals were severely mentally retarded (IQ from 25 to 30) and had behavioral issues. Heterozygous carriers had normal hair and were unaffected.