PANCREATIC CANCER, SUSCEPTIBILITY TO, 2

General Information (adopted from Orphanet):

Synonyms, Signs: PNCA2
Number of Symptoms 1
OrphanetNr:
OMIM Id: 613347
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0002894) Neoplasm of the pancreas 17 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Molecular genetics OMIM Ozcelik et al. (1997) investigated the contribution of germline BRCA2 mutations to the development of pancreatic cancer in 41 patients seen over a 4-month period, and selected without regard for family history. Mutations were identified in 2 patients ...
Population genetics OMIM Genetic studies of familial pancreatic cancer have led to the identification of mutations in the BRCA2 gene in approximately 12 to 20% of families, often in the absence of cases of breast or ovarian carcinoma (McWilliams et al., ...