LEUKEMIA, ACUTE LYMPHOBLASTIC

General Information (adopted from Orphanet):

Synonyms, Signs: LEUKEMIA, ACUTE LYMPHOCYTIC, SUSCEPTIBILITY TO, 1, INCLUDED
LEUKEMIA, B-CELL ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, INCLUDED
LEUKEMIA, T-CELL ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, INCLUDED
ALL LEUKEMIA, ACUTE LYMPHOBLASTIC, SUSCEPTIBILITY TO, 1, INCLUDED
LEUKEMIA, ACUTE LYMPHOBLASTIC, B-HYPERDIPLOID, SUSCEPTIBILITY TO, INCLUDED
ALL1, INCLUDED
Number of Symptoms 2
OrphanetNr:
OMIM Id: 613065
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Polygenic inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0006721) Acute lymphoblastic leukemia 7 / 7739
2
(HPO:0010982) Polygenic inheritance 14 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Acute lymphoblastic leukemia (ALL), also known as acute lymphocytic leukemia, is a subtype of acute leukemia, a cancer of the white blood cells. Somatically acquired mutations in several genes have been identified in ALL lymphoblasts, cells in the ...
Molecular genetics OMIM - Somatic Mutations

A t(9;22) translocation occurs in greater than 90% of chronic myelogeneous leukemia (CML; 608232), 25 to 30% of adult and 2 to 10% of childhood acute lymphoblastic leukemia, and rare cases of acute ...