ATRIAL FIBRILLATION, FAMILIAL, 6
General Information (adopted from Orphanet):
| Synonyms, Signs: |
ATFB6 |
| Number of Symptoms | 0 |
| OrphanetNr: | |
| OMIM Id: |
612201
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| ICD-10: |
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| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
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| Age of onset: |
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Disease classification (adopted from Orphanet):
| Parent Diseases: | No data available. |
Symptom Information:
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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Additional Information:
| Clinical Description OMIM |
Hodgson-Zingman et al. (2008) reported a 3-generation Caucasian family of northern European ancestry in which 11 members were diagnosed with atrial fibrillation at a mean age of 40 years, in 3 cases during pregnancy. There was a transition ... |
| Molecular genetics OMIM | Hodgson-Zingman et al. (2008) sequenced the candidate gene NPPA in a 3-generation family with atrial fibrillation and identified heterozygosity for a 2-bp deletion (108780.0001) that segregated with the disease and was not found in 560 controls. |