Valente et al. (2000) reported a large Indian kindred in which 13 individuals received a definite diagnosis of PKC. Family history indicated that 4 deceased individuals had been affected. The male:female ratio was 1.8:1. Age at onset ranged ... Valente et al. (2000) reported a large Indian kindred in which 13 individuals received a definite diagnosis of PKC. Family history indicated that 4 deceased individuals had been affected. The male:female ratio was 1.8:1. Age at onset ranged from 7 to 13 years, and all had brief attacks of up to 2 minutes consisting of dystonic or choreic movements precipitated by sudden movements, with a frequency of 1 to 20 episodes per day. None of the affected patients had a history of benign infantile convulsions. However, 5 family members, including 2 with PKC, had sporadic episodes of generalized tonic-clonic seizures in their teenage years that spontaneously resolved. Incomplete (75%) penetrance was reported. Spacey et al. (2002) reported further details of the Indian family. Six patients experienced sensory aura in the form of paresthesias involving the same part of the body. Nine of 17 affected members had spontaneous remission at an average age of 23.3 years.