MACULAR DEGENERATION, AGE-RELATED, 4

General Information (adopted from Orphanet):

Synonyms, Signs: ARMD4
Number of Symptoms 2
OrphanetNr:
OMIM Id: 610698
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Polygenic inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0007868) Age-related macular degeneration 4 / 7739
2
(HPO:0010982) Polygenic inheritance 14 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Molecular genetics OMIM Klein et al. (2005) performed a genomewide scan of 96 cases and 50 controls for polymorphisms associated with ARMD. They identified a risk allele (dbSNP rs380390) with a p value of less than 10(-7) that increased the likelihood ...