ESOPHAGITIS, EOSINOPHILIC, 1

General Information (adopted from Orphanet):

Synonyms, Signs: ESOPHAGITIS, EOSINOPHILIC
EE
EOE1
Number of Symptoms 11
OrphanetNr:
OMIM Id: 610247
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0002015) Dysphagia 301 / 7739
2
(HPO:0005263) Gastritis 9 / 7739
3
(HPO:0002588) Duodenal ulcer 15 / 7739
4
(HPO:0002013) Vomiting 191 / 7739
5
(HPO:0002592) Gastric ulcer 39 / 7739
6
(HPO:0011968) Feeding difficulties 240 / 7739
7
(HPO:0001508) Failure to thrive 454 / 7739
8
(OMIM) Food impaction 2 / 7739
9
(OMIM) Absence of eosinophilia in other intestinal segments 2 / 7739
10
(OMIM) Thickening of basal epithelial layer and elongation of papillae 2 / 7739
11
(OMIM) At least 24 eosinophils per high-power field on esophageal biopsy 2 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Eosinophilic esophagitis (EOE) has an incidence of approximately 1 per 10,000 people. Symptoms include difficulty feeding, failure to thrive, vomiting, epigastric or chest pain, dysphagia, and food impaction. Individuals with EOE are predominantly young males with a high ...
Clinical Description OMIM Eosinophilic esophagitis (EOE) is defined histologically by the presence of proliferative changes, including thickening of the basal epithelial layer and elongation of papillae, a minimum of 24 eosinophils per high-power field in the distal esophagus, and the absence ...