PREMATURE OVARIAN FAILURE 3

General Information (adopted from Orphanet):

Synonyms, Signs: POF3
Number of Symptoms 2
OrphanetNr:
OMIM Id: 608996
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0008209) Premature ovarian failure 19429596 IBIS 28 / 7739
2
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM Premature ovarian failure is defined by the cessation of ovarian function under the age of 40 years and is characterized by amenorrhea, hypoestrogenism, and elevated serum gonadotropin concentrations. It is believed that POF may be caused by either ...
Molecular genetics OMIM In 70 patients from New Zealand and Slovenia with premature ovarian failure, defined as cessation of menses for 6 or more months before the age of 40 years, Harris et al. (2002) screened the FOXL2 gene (605597) for ...