ASPERGER SYNDROME, SUSCEPTIBILITY TO, 2

General Information (adopted from Orphanet):

Synonyms, Signs: ASPG2
Number of Symptoms 15
OrphanetNr:
OMIM Id: 608631
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Multifactorial
Sporadic
[Omim]
Age of onset: Juvenile onset
[Omim]

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000733) Stereotypy 58 / 7739
2
(HPO:0000732) Inflexible adherence to routines or rituals 11 / 7739
3
(HPO:0000723) Restrictive behavior 11 / 7739
4
(HPO:0000728) Impaired ability to form peer relationships 8 / 7739
5
(HPO:0000735) Impaired social interactions 20 / 7739
6
(HPO:0000717) Autism 108 / 7739
7
(HPO:0000758) Impaired use of nonverbal behaviors 11 / 7739
8
(HPO:0000721) Lack of spontaneous play 11 / 7739
9
(HPO:0001426) Multifactorial inheritance 37 / 7739
10
(OMIM) Normal, timely language development 4 / 7739
11
(HPO:0003621) Juvenile onset 105 / 7739
12
(OMIM) Stereotyped, repetitive behavior 11 / 7739
13
(OMIM) Relatively higher cognitive abilities than classic autism 4 / 7739
14
(OMIM) Impaired use of nonverbal behaviors, such as eye-to-eye gaze, facial expression, body posture, and gestures 11 / 7739
15
(HPO:0003745) Sporadic 131 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Asperger syndrome is considered to be a form of childhood autism (see, e.g., 209850). The DSM-IV (American Psychiatric Association, 1994) specifies several diagnostic criteria for Asperger syndrome, which has many of the same features as autism. In general, ...
Clinical Description OMIM Anneren et al. (1995) reported a 10-year-old boy with Asperger syndrome. Development was normal until 3 years of age when he became anxious and withdrawn; he later developed depression and school phobic symptoms. Gross motor movements were clumsy, ...