ATRIAL FIBRILLATION, FAMILIAL, 1

General Information (adopted from Orphanet):

Synonyms, Signs: ATRIAL FIBRILLATION, AUTOSOMAL DOMINANT
ATFB1
Number of Symptoms 6
OrphanetNr:
OMIM Id: 608583
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0001649) Tachycardia 53 / 7739
2
(HPO:0011675) Arrhythmia 226 / 7739
3
(HPO:0005110) Atrial fibrillation 71 / 7739
4
(HPO:0001727) Thromboembolic stroke 4 / 7739
5
(OMIM) Atrial fibrillation, isolated 2 / 7739
6
(OMIM) Thromboembolic stroke may occur 2 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Atrial fibrillation is the most common sustained cardiac rhythm disturbance, affecting more than 2 million Americans, with an overall prevalence of 0.89%. The prevalence increases rapidly with age, to 2.3% between the ages of 40 and 60 years, ...
Clinical Description OMIM Brugada et al. (1997) reported a Spanish family in which 10 members spanning 3 generations had atrial fibrillation segregating as an autosomal dominant trait. Nine family members had chronic atrial fibrillation and 1 had paroxysmal atrial fibrillation. Two ...