PULMONARY DISEASE, CHRONIC OBSTRUCTIVE

General Information (adopted from Orphanet):

Synonyms, Signs: PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, RATE OF DECLINE OF LUNG FUNCTION IN, INCLUDED
COPD, SEVERE EARLY-ONSET, INCLUDED
COPD PULMONARY DISEASE, CHRONIC OBSTRUCTIVE, SEVERE EARLY-ONSET, INCLUDED
Number of Symptoms 1
OrphanetNr:
OMIM Id: 606963
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0006510) Chronic obstructive pulmonary disease 19 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Chronic obstructive pulmonary disease (COPD) is a common, complex disorder associated with substantial morbidity and mortality. COPD is defined by irreversible airflow obstruction due to chronic bronchitis, emphysema, and/or small airways disease. Airflow obstruction is typically determined by ...
Molecular genetics OMIM Among 201 smokers, Yamada et al. (2000) found an association between emphysema and a longer length polymorphism in the promoter region of the HMOX1 gene (141250.0003). The proportion of genotypic frequencies in the group with longer alleles was ...