VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1

General Information (adopted from Orphanet):

Synonyms, Signs: VAMAS1
SYSTEMIC LUPUS ERYTHEMATOSUS, VITILIGO-RELATED
VITILIGO
VTLG
SLEV1
Number of Symptoms 2
OrphanetNr:
OMIM Id: 606579
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Polygenic inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0001045) Vitiligo 13 / 7739
2
(HPO:0010982) Polygenic inheritance 14 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Description: (OMIM) Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associated with an elevated risk of other autoimmune diseases. It is a genetically complex disorder involving multiple ...
Clinical Description OMIM McKusick (1983) observed a family in Maine in which vitiligo occurred in many members. The occurrence of halo nevi (see 234300) as a striking feature of the proband and some others suggested that this is a manifestation of ...