SCHIZOPHRENIA 10
General Information (adopted from Orphanet):
| Synonyms, Signs: |
CATATONIA, PERIODIC SCZD10 SCHIZOPHRENIA SUSCEPTIBILITY LOCUS, CHROMOSOME 15q15-RELATED |
| Number of Symptoms | 16 |
| OrphanetNr: | |
| OMIM Id: |
605419
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| ICD-10: |
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| UMLs: |
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| MeSH: |
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| MedDRA: |
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| Snomed: |
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Prevalence, inheritance and age of onset:
| Prevalence: | No data available. |
| Inheritance: |
Autosomal dominant inheritance [Omim] |
| Age of onset: |
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Disease classification (adopted from Orphanet):
| Parent Diseases: | No data available. |
Symptom Information:
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(HPO:0000298) | Mask-like facies | 44 / 7739 | ||||
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(HPO:0005324) | Disturbance of facial expression | 2 / 7739 | ||||
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(HPO:0000738) | Hallucinations | 60 / 7739 | ||||
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(HPO:0000725) | Psychotic episodes | 6 / 7739 | ||||
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(HPO:0000746) | Delusions | 21 / 7739 | ||||
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(HPO:0100753) | Schizophrenia | 20 / 7739 | ||||
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(OMIM) | Derangements of facial expression | 1 / 7739 | ||||
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(OMIM) | Excited catatonia | 1 / 7739 | ||||
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(OMIM) | Psychomotor disturbances during acute psychotic outbursts | 1 / 7739 | ||||
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(OMIM) | Schizophrenia, atypical | 1 / 7739 | ||||
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(OMIM) | Iterations | 1 / 7739 | ||||
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(HPO:0000006) | Autosomal dominant inheritance | 2518 / 7739 | ||||
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(OMIM) | Diminished incentive | 1 / 7739 | ||||
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(MedDRA:10061991) | Grimacing | 4 / 7739 | ||||
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(OMIM) | Stuporous catatonia | 2 / 7739 | ||||
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(OMIM) | Parakinesis | 1 / 7739 |
Associated genes:
ClinVar (via SNiPA)
| Gene symbol | Variation | Clinical significance | Reference |
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Additional Information:
| Clinical Description OMIM |
A clinical subtype of schizophrenia, termed periodic catatonia, is characterized by derangements of facial expression and gestures, so-called psychomotor disturbances (Leonhard, 1999). Catatonia can exhibit 2 psychotic poles: psychomotor excitement and inhibition. Features include grimacing or mask-like facies, ... |