Familial advanced sleep-phase syndrome

General Information (adopted from Orphanet):

Synonyms, Signs: FASPS
Number of Symptoms 9
OrphanetNr: 164736
OMIM Id: 604348
615224
ICD-10: G47.2
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant
[Orphanet]
Age of onset: Childhood
Adolescent
[Orphanet]

Disease classification (adopted from Orphanet):

Parent Diseases: Rare genetic neurological disease
 -Rare genetic disease
Sleep disorder
 -Rare neurologic disease

Symptom Information: Sort by abundance 

1
 (HPO:0002360) Sleep disturbance Very frequent [Orphanet] 113 / 7739
2
 (HPO:0002315) Headache Occasional [Orphanet] 175 / 7739
3
 (HPO:0100851) Abnormal emotion/affect behavior Frequent [Orphanet] 85 / 7739
4
 (HPO:0006979) Sleep-wake cycle disturbance hallmark [HPO] 5 / 7739
5
 (HPO:0002027) Abdominal pain Occasional [Orphanet] 184 / 7739
6
 (HPO:0002019) Constipation Occasional [Orphanet] 194 / 7739
7
 (HPO:0002592) Gastric ulcer Occasional [Orphanet] 39 / 7739
8
 (HPO:0002045) Hypothermia Very frequent [Orphanet] 27 / 7739
9
 (HPO:0000006) Autosomal dominant inheritance 2518 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information: