SCHIZOPHRENIA 4

General Information (adopted from Orphanet):

Synonyms, Signs: SCZD4
SCHIZOPHRENIA SUSCEPTIBILITY LOCUS, CHROMOSOME 22q11-RELATED
Number of Symptoms 5
OrphanetNr:
OMIM Id: 600850
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance: Autosomal dominant inheritance
[Omim]
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0100753) Schizophrenia 20 / 7739
2
(HPO:0001939) Abnormality of metabolism/homeostasis 328 / 7739
3
(OMIM) Interstitial deletion of 22q11 1 / 7739
4
(HPO:0000006) Autosomal dominant inheritance 2518 / 7739
5
(OMIM) Schizophrenia susceptibility 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Molecular genetics OMIM Mimmack et al. (2002) screened a custom-made cDNA array comprising 300 candidate schizophrenia genes using probes derived from prefrontal cortex tissue of 10 schizophrenia and 10 control brains. The screen revealed a 2.6-fold upregulation of apolipoprotein L1 (APOL1; ...