GLAUCOMA-RELATED PIGMENT DISPERSION SYNDROME

General Information (adopted from Orphanet):

Synonyms, Signs: PIGMENT DISPERSION SYNDROME
GLAUCOMA, PIGMENT-DISPERSION TYPE
GPDS1
PDS
Number of Symptoms 8
OrphanetNr:
OMIM Id: 600510
ICD-10:
UMLs:
MeSH:
MedDRA:
Snomed:

Prevalence, inheritance and age of onset:

Prevalence: No data available.
Inheritance:
Age of onset:

Disease classification (adopted from Orphanet):

Parent Diseases: No data available.

Symptom Information: Sort by abundance 

1
(HPO:0000545) Myopia 286 / 7739
2
(HPO:0012108) Primary open angle glaucoma 6 / 7739
3
(HPO:0000648) Optic atrophy 238 / 7739
4
(HPO:0011462) Young adult onset 7 / 7739
5
(OMIM) Frequent myopia 1 / 7739
6
(OMIM) Permanent loss of sight 1 / 7739
7
(OMIM) Pigment-dispersion type open-angle glaucoma 1 / 7739
8
(OMIM) Pigment granule depositon from iris epithelium to other ocular structures 1 / 7739

Associated genes:

ClinVar (via SNiPA)

Gene symbol Variation Clinical significance Reference

Additional Information:

Clinical Description OMIM The pigment dispersion syndrome with open-angle glaucoma usually affects individuals under the age of 30 years. In addition to the typical optic nerve degeneration seen in all forms of glaucoma, the pigment dispersion syndrome is characterized by distinctive ...