Search Results for "NOS3" - 229 interactions found in 109 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
629
3341 NOS3 interacts (colocalizes) with HSP90B1
17855507 Amyotrophic lateral sclerosis
1,176
7791 ob/ob mouse NOT affects_expression of NOS3
15805118 Diabetes mellitus, type II
Insulin resistance
1,188
7892 obesity, high-fat diet-induced NOT affects_expression of NOS3 in skeletal muscle
11590438 Diabetes mellitus, type II
Insulin resistance
1,375
9419 PTGER2 affects_expression of NOS3 in lumbar spinal cord; in SOD1G93A mutant mice
18825663 Amyotrophic lateral sclerosis
2,036
16194 REN decreases_activity of NOS3 in aorta; after insulin stimulation, in Ren-2 rats
16196 Valsartan increases_activity of NOS3 in aorta; in Ren-2 rats, after insulin stimulation
16198 Tempol increases_activity of NOS3 in aorta; in Ren-2 rats, after insulin stimulation
17533199 Diabetes mellitus, type II
Insulin resistance
2,118
17310 Nebivolol increases_activity of NOS3
17311 Atenolol NOT increases_activity of NOS3
18772860 Diabetes mellitus, type II
Insulin resistance
2,119
17386 Angiotensin II decreases_activity of NOS3 via uncoupling of the active homodimer
17387 Nebivolol NOT decreases_activity of NOS3 after angiotensin II treatment
16940222 Diabetes mellitus, type II
Insulin resistance
2,122
17393 HDL increases_activity of NOS3 in aorta; via dimerization of NOS3
19273745 Diabetes mellitus, type II
Insulin resistance
2,124
17412 NOS3 affects_activity of relaxation of vascular smooth muscle if induced by nebivolol
16116070 Diabetes mellitus, type II
Insulin resistance
2,125
17442 Nebivolol increases_activity of NOS3 in obese Zucker rats
20176997 Diabetes mellitus, type II
Insulin resistance
2,130
17530 L-NAME decreases_activity of NOS3
17531 NOS3 affects_quantity of NO
17532 NOS3 decreases_quantity of BACE1
17533 NOS3 decreases_quantity of Amyloid beta peptide
21127294 Alzheimer disease
2,131
17568 Streptozocin-induced diabetes decreases_phosphorylation of NOS3 at Ser1177
17572 Telmisartan decreases_phosphorylation of NOS3 at Ser1177, in streptozotocin-diabetic rats
17573 Telmisartan NOT decreases_activity of NOS3 in streptozotocin-diabetic rats
18539157 Diabetes mellitus, type II
Diabetes mellitus, type I
Insulin resistance
2,135
17578 NOS3 affects_quantity of NOS3 homodimer if NOS3 is overexpressed
17580 GCH1 NOT affects_expression of NOS3 if GCH1 is overexpressed
17581 NOS3 affects_quantity of Tetrahydrobiopterin if NOS3 is overexpressed
17604 NOS3 increases_quantity of NO if NOS3 is overexpressed
17606 Tetrahydrobiopterin affects_activity of NOS3
16179591 Diabetes mellitus, type II
Insulin resistance
2,138
17648 NOS3 affects_activity of vasodilation if induced by HDL
17650 AKT1 increases_phosphorylation of NOS3 at Ser1177, if induced by HDL
17667 Sphingosylphosphorylcholine increases_activity of NOS3
17668 Sphingosine 1-phosphate increases_activity of NOS3
17669 Lysosulfatide increases_activity of NOS3
17683 AKT1 increases_activity of NOS3 via phosphorylation at Ser1177
14966566 Diabetes mellitus, type II
Insulin resistance
2,139
17701 AKT1 increases_activity of NOS3
17714 AKT1 increases_phosphorylation of NOS3 at Ser1177
17715 Ca2+ increases_activity of NOS3
10376603 Diabetes mellitus, type II
Insulin resistance
2,141
17766 Sphingosine 1-phosphate increases_activity of NOS3
17770 CAMKK2 affects_activity of NOS3 if induced by S1P or HDL
17772 HDL increases_activity of NOS3
17777 STK11 affects_activity of NOS3 if SR-BI-mediated
17816 AMPK increases_activity of NOS3
17817 NOS3 decreases_expression of VCAM1
17818 NOS3 decreases_activity of monocyte adhesion
17829 phosphatidylinositol 3-kinase signaling increases_activity of NOS3
20018878 Diabetes mellitus, type II
Insulin resistance
3,558
33124 NOS3 affects_activity of atherosclerotic lesions
33125 NOS3 affects_activity of Alzheimer disease
16973241 Alzheimer disease
Metabolic
Atherosclerosis
3,752
36504 Diabetes mellitus, type II decreases_expression of NOS3 in kidney
36505 Pioglitazone increases_expression of NOS3 in kidney; in diabetic mice
16609149 Diabetes mellitus, type II
Insulin resistance
4,181
43013 Schizophrenia decreases_activity of NOS3 in postmortem brain
12363386 Schizophrenia
4,534
45446 NOS3 affects_activity of abnormal mitochondrial physiology
45512 NOS3 affects_activity of Mitochondrial respiratory chain complex I
22138560 Diabetes mellitus, type II
Developmental
Insulin resistance
Glaucoma, primary open angle
4,699
46636 NOS3 decreases_quantity of Arginine
46642 NOS3 increases_quantity of NO
46645 NOS3 increases_quantity of Citrulline
7510950 Metabolic
Cardiovascular disease
4,710
46689 NOS3 increases_quantity of NO in vascular endothelial cells
7536096 Cardiovascular disease
4,713
46707 NOS3 decreases_quantity of Homoarginine to produce NO
24004504 Stroke, ischemic
Cardiovascular disease
4,714
46717 NOS3 is_expressed_in aortic endothelial cell and is responsible for steady state NO production
23980179 Cardiovascular disease
4,717
46746 CRP decreases_expression of NOS3 by increasing the expression of RAGE
46747 CRP decreases_quantity of NOS3 by increasing the expression of RAGE
46755 AGER decreases_expression of NOS3 by increasing the ROS level
46756 AGER decreases_quantity of NOS3 by increasing the ROS level
22301267 Cardiovascular disease
4,724
46791 NOS3 is localized in caveola
46798 SCARB1 increases_activity of NOS3 by regulating the HDL-cholesterol transport into caveolae
46803 HDL increases_activity of NOS3 by increasing the cholesterol content in caveolae
12922018 Cardiovascular disease
Atherosclerosis
4,725
46792 HDL increases_activity of NOS3
46809 HDL increases_activity of NOS3 in caveola
46811 LDL NOT affects_activity of NOS3 in caveola
46821 SCARB1 increases_activity of NOS3
46836 protein kinase B signaling increases_activity of NOS3 after activation of SCARB1 with HDL
46837 MAPK cascade increases_activity of NOS3 after activation of SCARB1 with HDL
46846 SCARB1 increases_phosphorylation of NOS3 via PI3K-Akt signaling
12922018 Cardiovascular disease
Atherosclerosis
4,736
47038 EDN1 increases_quantity of NOS3 via activation of ETB receptors and PI3K
50712 EDN1 increases_expression of NOS3 via activation of ETB receptors and PI3K
15113749 Cardiovascular disease
4,737
46857 EDN1 increases_expression of NOS3 via ETA receptors (EDNRA)
47040 EDNRA increases_expression of NOS3 if ETA has been induced by endothelin-1
10519149 Cardiovascular disease
4,739
46859 VEGFA increases_expression of NOS3
46871 sFLT1 decreases_activity of NOS3 via antagonizing VEGFA activity
46872 sFLT1 decreases_phosphorylation of NOS3
21139021 Preeclampsia/eclampsia 1
Cardiovascular disease
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