Search Results for "APOE" - 224 interactions found in 97 entries.

Entry-ID
Interactor1 (Subject) Interaction type Interactor2 (Object) additional information
PubMed-ID
Diseases
569
2986 APOE decreases_quantity of APP in plasma
10670439 Alzheimer disease
1,207
13429 high-fat diet increases_expression of APOE in resident adipose tissue macrophages; in male mice
17192460 Diabetes mellitus, type II
Insulin resistance
1,893
14550 astrocyte increases_quantity of APOE in CNS; via secretion
14552 microglia increases_quantity of APOE in CNS; via secretion
14575 protein lipidation affects_activity of APOE
14585 APOE interacts (colocalizes) with neurofibrillary tangles in AD patients
129151 APOE lipidation affects_activity of APOE
20170744 Alzheimer disease
2,016
15976 LRP6 affects_activity of APOE in AD
17517621 Alzheimer disease
2,227
18842 FTO interacts (colocalizes) with APOE
21098976 Alzheimer disease
2,410
21837 APOE is localized in astrocyte
21838 T 0901317 increases_expression of APOE
21562267 Alzheimer disease
2,533
23593 APOE affects_activity of cholesterol metabolic process in brain
23600 APOE affects_activity of triglyceride metabolic process in body
23601 APOE affects_activity of lipoprotein transport into brain
23602 APOE interacts (colocalizes) with Amyloid beta peptide
23805 ABCA1 affects_quantity of APOE by stimulating efflux of excess intracellular cholesterol to extracellular lipid acceptors, including unlipidated APOE
23806 ABCA1 affects_processing of APOE
23807 ABCA1 affects transport of APOE
21448224 Alzheimer disease
2,773
25687 GIPR NOT affects_expression of APOE in adrenal cortex
22043004 Diabetes mellitus, type II
Insulin resistance
3,558
33096 APOE affects_activity of Alzheimer disease
33097 APOE affects_activity of atherosclerotic lesions
16973241 Alzheimer disease
Metabolic
Atherosclerosis
3,674
35505 Alzheimer disease decreases_quantity of APOE
22801742 Alzheimer disease
3,699
36044 LEP affects_activity of APOE in AD animal models
22329649 Alzheimer disease
3,971
40393 APOE NOT affects_activity of Multiple sclerosis in relapsing remitting multiple sclerosis (RRMS)
21163235 Multiple sclerosis
4,201
43119 Diabetes mellitus, type II increases_expression of APOE in blood
23337395 Diabetes mellitus, type II
Insulin resistance
4,866
47918 APOE decreases_quantity of O2-
19465644 Metabolic
Cardiovascular disease
4,914
48569 APOE increases_transport of Cholesterol
18308724 Metabolic
4,933
48750 Amyloid beta peptide interacts (colocalizes) with APOE
48794 Cholesterol increases_expression of APOE
12206998 Metabolic
4,934
48760 APOE affects_activity of cholesterol import
3283935 Metabolic
4,935
48789 APOE interacts (colocalizes) with Amyloid beta peptide in vitro
8089103 Metabolic
4,936
48790 APOE interacts (colocalizes) with Amyloid beta peptide
7619525 Metabolic
5,086
50066 Olanzapine decreases_expression of APOE in white adipose tissue
24667776 Diabetes mellitus, type II
Schizophrenia
Insulin resistance
6,097
57028 Pseudoxanthoma elasticum decreases_expression of APOE in dermal fibroblasts
25064003 Pseudoxanthoma elasticum
6,172
57707 Metformin NOT affects_expression of APOE
18501722 Diabetes mellitus, type II
Insulin resistance
6,803
66099 Stroke, ischemic increases_quantity of APOE in blood serum; in acute ischemic stroke
25807139 Stroke, ischemic
6,826
66426 WFS1 affects_expression of APOE
27053292 Diabetes mellitus, type II
Wolfram syndrome 1
Insulin resistance
6,894
67327 APOE affects_activity of lipid metabolic process
67339 APOE increases_transport of Lipoprotein in brain ; via LRP1
67342 APOE increases_activity of maintenance of permeability of blood-brain barrier
27470930 Diabetes mellitus, type II
Insulin resistance
7,308
71693 APOE affects_quantity of Sphingosine 1-phosphate in hippocampus; via secretion; the quantity is depending on the APOE isoform.
71717 Sphingosine 1-phosphate interacts (colocalizes) with APOE in the CNS; in high density lipoprotein (HDL) complexes
24456642 Alzheimer disease
Metabolic
7,416
136876 APOE affects_expression of CYP7A1 in ApoE KO mice; 2.43 fold, when male ApoE-KO mice were fed an atherogenic diet supplemented with or without 2% phytosterol mixtures for 14 weeks.
136877 APOE affects_expression of CYP7B1 in ApoE KO mice; 1.67 fold, when male ApoE-KO mice were fed an atherogenic diet supplemented with or without 2% phytosterol mixtures for 14 weeks.
136878 APOE affects_expression of LPIN2 in ApoE KO mice; 1.56 fold, when male ApoE-KO mice were fed an atherogenic diet supplemented with or without 2% phytosterol mixtures for 14 weeks.
136879 APOE affects_expression of LPIN1 in ApoE KO mice; 2.97 fold, when male ApoE-KO mice were fed an atherogenic diet supplemented with or without 2% phytosterol mixtures for 14 weeks.
136880 APOE affects_expression of HMGCR in ApoE KO mice; 2.18 fold, when male ApoE-KO mice were fed an atherogenic diet supplemented with or without 2% phytosterol mixtures for 14 weeks.
136881 APOE affects_expression of HMGCS1 in ApoE KO mice; 1.61 fold, when male ApoE-KO mice were fed an atherogenic diet supplemented with or without 2% phytosterol mixtures for 14 weeks.
18155511 Alzheimer disease
Metabolic
7,436
136875 APOE affects_activity of atherosclerotic lesions in ApoE-/- mouse; when angiotensin II-induced
26296466 Atherosclerosis
Inflammation
7,453
73369 Estradiol increases_quantity of APOE in liver and in brain; of the male mice
19239128 Metabolic
7,454
73373 ESR1 increases_expression of APOE in hippocampus; in ovariectomized (OVX) female rats
73375 ESR2 decreases_expression of APOE in hippocampus; in ovariectomized (OVX) female rats
17077142 Alzheimer disease
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