How to query CIDeRplus

• Per default the search space includes all diseases and all types of data. Queries are not case-sensitive and search all database content that includes the query term (e.g. Mito is sufficient to find everything concerning mitochondria). This type of query is highly unspecific as it includes also information such as gene/protein name synonyms and authors names from referenced literature.
• The first box of the search options (Diseases) allows to restrict the search space for the disease/-s of interest.
• The second box of the search options (Field) allows searching within a specific type of data, e.g. only within genes/proteins, biological processes etc.
• Combined queries can be performed by using Refine query. By clicking on Refine query a second search field is opened. A drop-down menu allows combining the two queries with the Boolean operators AND, OR and NOT.
• The search space can be restricted by setting the search term into double quotes (e.g. "MAPK1" will not find MAPK14 which would happen without quotes)
• The character for wild-card is '%'. It can also be used in a double-quoted search term.

Examples:

cell cycle	Finds every term that contains the words 'cell' and 'cycle' anywhere (also synonyms!), i.e. you will retrieve 'cell cycle', 're-entry into mitotic cell cycle' but also 'pyridoxal phosphate biosynthetic process'. The latter is a GO term that includes the words 'cell' and 'cycle' in higher level GO terms (GO:0044249 : cellular biosynthetic process and GO:0046483 : heterocycle metabolic process)
"cell cycle"	Finds only exactly 'cell cycle' but not 're-entry into mitotic cell cycle' or 'pyridoxal phosphate biosynthetic process'
"%cell cycle"	Finds 'cell cycle' and 're-entry into mitotic cell cycle' but not 'pyridoxal phosphate biosynthetic process'. "%cell cycle%" would, in addition, find terms like 'cell cycle arrest' or all textual comments that include 'cell cycle'.