General Information:

Id: 976 (click here to show other Interactions for entry)
Diseases: Alzheimer disease - [OMIM]
Prion disease
Mammalia
review
Reference: Cisse M and Mucke L(2009) Alzheimers disease: A prion protein connection. Nature 457: 1090-1091 [PMID: 19242462]

Interaction Information:

Comment The enzyme alpha-secretase precludes Abeta production by cleaving the Abeta precursor protein APP within the Abeta domain.
Formal Description
Interaction-ID: 6030

gene/protein

Alpha-secretase

increases_processing of

gene/protein

APP

Drugbank entries Show/Hide entries for APP