General Information:

Id: 8,605 (click here to show other Interactions for entry)
Diseases: Gastrointestinal
Metabolic
Mammalia
review
Reference: Blacher E et al.(2017) Microbiome-Modulated Metabolites at the Interface of Host Immunity J. Immunol. 198: 572-580 [PMID: 28069752]

Interaction Information:

Comment Angiotensin I converting enzyme 2 (ACE2) controls the levels of neutral amino acids in the intestine, including Trp. A deficiency in ACE2 results in higher susceptibility for intestinal inflammation and an altered gut microbial composition.
Formal Description
Interaction-ID: 88900

gene/protein

ACE2

affects_quantity of

drug/chemical compound

Tryptophan

Drugbank entries Show/Hide entries for ACE2
Comment Angiotensin I converting enzyme 2 (ACE2) controls the levels of neutral amino acids in the intestine, including Trp. A deficiency in ACE2 results in higher susceptibility for intestinal inflammation and an altered gut microbial composition.
Formal Description
Interaction-ID: 88903

gene/protein

ACE2

decreases_activity of

Drugbank entries Show/Hide entries for ACE2