General Information:

Id: 7,455 (click here to show other Interactions for entry)
Diseases: Metabolic
Homo sapiens
Reference: Nathan BP et al.(2004) Estrogen facilitates neurite extension via apolipoprotein E in cultured adult mouse cortical neurons Endocrinology 145: 3065-3073 [PMID: 15033916]

Interaction Information:

Comment Estradiol had no effect on neurite outgrowth from mice lacking the ApoE gene or when only ApoE4, the isoform of ApoE that is associated with increased risk of neurological disease, was exogenously supplied.
Formal Description
Interaction-ID: 73398

drug/chemical compound


NOT affects_expression of

gene/protein mutant

APOE (isoform E4)

in cultured adult mouse cortical neurons
Drugbank entries Show/Hide entries for Estradiol