General Information:

Id: 7,302 (click here to show other Interactions for entry)
Diseases: Cardiovascular disease
Major depressive disorder - [OMIM]
Homo sapiens
article
Reference: Zill P et al.(2012) DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression PLoS ONE 7 [PMID: 22808171]

Interaction Information:

Comment A significant inverse correlation between the concentrations of the inflammatory CVD risk markers ICAM-1, E-selectin and P-selectin and the degree of ACE promoter methylation in MD patients could be demonstrated.
Formal Description
Interaction-ID: 71734

gene/protein

ACE

affects_quantity of

gene/protein

SELE

via hypermethylation of a CpG island in the proximal ACE promoter
Drugbank entries Show/Hide entries for ACE or SELE