General Information:

Id: 5,787 (click here to show other Interactions for entry)
Diseases: Lung disease
Pulmonary fibrosis, idiopathic - [OMIM]
Mus musculus
bleomycin model of murine fibrosis, Lrp5 -/- mice
article
Reference: Lam AP et al.(2014) Wnt coreceptor Lrp5 is a driver of idiopathic pulmonary fibrosis Am. J. Respir. Crit. Care Med. 190: 185-195 [PMID: 24921217]

Interaction Information:

Comment Elevated TGF-beta levels are involved in the development of pulmonary fibrosis.
Formal Description
Interaction-ID: 54624

gene/protein

TGFB1

increases_activity of

phenotype

pulmonary fibrosis

Drugbank entries Show/Hide entries for TGFB1